I think its possible that some relatively simple model will be found to explain this relationship, but I also think its possible that the mechanics of intelligence are simply complex enough that the explanation is something inaccessible with our current level of understanding. And we know that theres differential infant mortality rates. This confuses me a little. Theres probably not anyone working in math right now who is any smarter than Gauss was. There is yet more. In sum, these findings suggest that neurodevelopmental social impairment exists in varied forms with varied etiologies and varied pathophysiologies, but the ASD diagnostic criteria do not identify a valid entity, Link to the entire piece https://link.springer.com/content/pdf/10.1007/s40489-016-0085-x.pdf. This always seemed nonsensical to me, because muscle is muscle; if two people are equally large, it shouldnt matter whether they were born that way or got that way through exercise. Im not suggesting this accounts for the high/low intelligence as the sample size was small. They've also got a blog about what they're doing here. Lets say for example that parameter A is the learning rate in the part of the brain that deals with reasoning. (I.e. They all share the same hunger for mathematics, and if you get to know those who seem normal on the surface, you find out that they have some interesting hobbies as well. There are maybe as many as 1000 of them in the Western world, and none of them would want to ever hang out with us because they are smart enough to know that their time would be better spent managing their billion-dollar corporations and/or governments. It is very, very smart, but nobody dares reproduce naturally anymore, not because the equipment doesnt work, but because genetic engineering means everyone pushed every single one of these levers to the setting marked beyond this point, there be dragons, and at least half their kids would die or come out completely non-functional if they tried it. In the 1800s, the average US man weighed about 155 lbs. In the graph of relatives, are autists typically on the border or inside of high-IQ regions? Im going to interpret fitting in as being liked.. But such an explanation is premature. and b) people diagnosed with autism using current criteria are quite prevalent in the community and presumably functioning in their communities. I am one of those people who has to run emulators to appear socially normal. This is the only study I know that has actually measured autism rates in the general public. I recall it because the lowest functioning children all had loser fathers. But if you pile on enough of the genes that increase IQ by increasing your head circumference, you will get a kid with such a huge head that his neck wont support it and his heart and lungs cant keep his giant brain in oxygenated blood, and hell die as a baby. While their exact numbers are doubtful, I think the overall finding that common familial genes are much more important than rare de novo mutations survives and is important. The Tower vs Foundation model is probably an oversimplification of something like this. I dont think there was much correlation at all with years of formal education, and the paths their lives and careers took are almost unimaginable now. Even if intelligence where a little lower we would have a lot more genius given the increase in population. But >39 repeats means risk of the disease. Why on Earth people take a decomposition of intelligence quotient such as the v-p-r, while itself fairly reasonable sounding but also very broad, and take seriously attempts to shoehorn that as the biological mechanism behind a very handwavy metaphor-like explanation such as tower and foundation?It is blatantly obvious that v-p-r is a very crude model that should not make sense. I guess it depends on how you define weirdness; I define it as having interests, beliefs, or though processes that are significantly different than most people I dont think Ive encountered any extremely intelligent people for whom none of the above are the case. Article I wrote about Sleep Apnea, Autism, and Neurodiversity. What do So, one can see how this would obviously lead to an increase in autoimmunity, but in one of the later chapters AEoA, Velazquez-Manoff also shows how autism (a least a lot of the time) is an inflammatory condition: for instance, autopsies uniformly showing neural inflammation, people with ASDs are more likely to develop autoimmune diseases than the general population and are more likely to have family members with autoimmune diseases, and for a few subjects treatment with immune-modulating intestinal worms providing some symptom relief even. My bosses at my last job (normal modulo their ethnic origin). We dont let people who are neither smart nor charismatic hang out with us, and people who are both smart and charismatic dont want to hang out with us. The fact that nobody has noticed and studied an effect in a subgroup is evidence that the subgroup does not have a large effect. Four things that make one delicious combination. Think about it this way: When most other people behave incomprehensible for you because they dont see the same emotional nuances and act on their impulses, it is hard to learn social customs, even though you theoretically have the potential to be very skilled socially. Slate Star Codex - Wikipedia I dont have time to go through all the links this morning but wanted to add some more studies. A PhD in particle physics at 15 is incredibly impressive, but a programmer starting out of college at an FAANG who saves a bit will be a millionaire by 30. If e.g. Given that many drugs both medical and recreational appear to affect similarly subtle parameters broadly through relatively simple molecules, theres no reason to assume they cant be much more specifically fine-tuned through genetics. In particular, this aligns well with the observation that de novo variants are more frequently observed in ASD cases with intellectual disability compared to cases without comorbid intellectual disability, that IQ correlates positively with family history of psychiatric disorders92 and that severe intellectual disability (encompassing many syndromes that confer high risk to ASD) show far less heritability than is observed for mild intellectual disability93, intelligence in general94 and ASDs. The people who have the genes to be the smartest humans can hit somewhere close to their potential by happening to have the right environment, enough food and no development-stunting diseases during critical times, etc. However, once it exceeds a certain threshold, the network starts learning things that dont make any sense, and then when it tries to correct those mistakes it goes too far in the other direction again. I would recommend having girls through IVF if that is legally allowed in your jurisdiction? About 13% of autistic children (in this sample from whatever social stratum they took their sample from) have fathers who are engineers, compared to only 5% of a group of (presumably well-matched?) (Always Sunny parodied this phenomenon with Mac, who only works out his glamour muscles.). Dunno, but you dont need to know the exact structure of the genotype to phenotype map to check whether the assumption is empirically correct. Thus, the question under discussion becomes does every highly intelligent person have some of these autism-linked genes, or are there other paths to high intelligence that do not involve these genes?. Most of my coworkers (except for the youngest ones) are married, and many have children. * Have a sense of entitlement and require constant, excessive admiration Seattle Anxiety Specialists are a therapy practice helping people overcome anxiety and related mental health issues (eg GAD, OCD, PTSD) through evidence based interventions and self-exploration. We were grouped with autistic including low functioning autistics. Your model of too much of a good thing seems to, to my non-doctor, non-expert mind, fit perfectly. Because he was as skilled as me, and had real muscles. However, I couldnt beat the Sophomore at 130 who was my workout partner in the weight room and only had 5-10 lbs on me in most lifts. That seems too low, based on my interactions with her: shes not so much slow as odd, so it may very well be that the test isnt a good measure. (And maybe theres some kind of subtype of autism > size of correlation thing happening, too. Given the numerous different genetic correlates to autism, if one wants to preserve the diagnostic validity of autism by finding a single etiology, one might hypothesize that all of these genes affect a narrow set of brain circuitry in a similar way, but as discussed in the Waterhouse paper people have tried to do this and (per her lit review) failed to do so. Precision of it? 47.3k members in the slatestarcodex community. The optimal value is at 10.0 (for example). Many definitions of autism center around forms of poor functioning which are correlated with low intelligence. I have a day job and SSC gets free hosting, so don't feel pressured to contribute. I was a bit of an outlier in my family, and didnt really find a peer group I fitted in with until university. Ive only found one paper that takes this model completely seriously and begins speculating on the nature of the foundation. She is a university qualified computer systems engineer. Karpinksi et al. Your argument also seems tautological to an extent; if youre defining normal as someone who thinks like a normal person, thats basically the equivalent of describing an object as being shaped like itself. Knowing how much of the genetic variance in intelligence (say IQ for an easy measure) is additive is probably good enough to figure out how off the purely linear assumption is. Note that billionaires in America are still vulnerable to (using a topical example) wealth taxes, and abroad billionaires in Russia / China must play the cuddle up to Putin / Xi or die / get put in a camp game. Research suggests that there is an ongoing reversed Flynn effect, i.e. (2) genes that promote autism are being selected for I then play out both parts of the conversation from memory as their mouth gapes open.). ASD has no reliable early predictor, no unitary developmental course, no unitary life outcome, no unitary recurrence risk, no unitary pattern of BAP features, and no standard homogeneous subgroups. (PDF link) This was the link from Wikipedia; Im not sure where else to look for the paper. Why do you think they arent sperging out about sportsball? If so, then the top-level geniuses may well have something else going on upstairs to enhance their intelligence, some other difference from the norms, that isnt part of the complex of IQ/autism risk genes. (Is that still seen as credible? Social rituals are incredibly important though, humans are social animals. If the genetic risk factors for high-functioning and low-functioning autism have a lot of overlap, as Scott suggests, then that strongly implies a connection in etiology. And autistic people have more health issues than non-autistic people do. My son was measured using the full Weschler and most of his scores were 96-99th percentile (thats VERY high). If I personally were one of these hypothetical genius scientists in possession of technology that could reshape the world, I think that the most optimal strategy for me would be to offer this technology to the U.S. in exchange for a large sum of money say, $50 million. Its not about purely not working out, although I would say natural strength is a part of it (almost every wrestler can increase his in-match power through lifting still), its about the muscles being coordinated and firing at the right angles and right times to actually accomplish something. One big category would be selection bias due to diagnosis bias. Book Review: The Perfect Health Diet Black and Hispanic children are less likely to be diagnosed with autism than white kids, but a lot of black, Hispanic, and Native American kids have various forms of learning disabilities. But even adjusting for these factors, the autism low intelligence correlation seems too strong to dismiss.
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