Names of Justicia Betonica in various languages of the world are also given. International Journal of Phytomedicine and Phytotherapy, Clinical Phytoscience Therefore,it is imperative to investigate the effects of the plant on the essential biochemical indices in diabetic rats so as to establish its safety. Photomicrograph of a liver sections stained with Haematoxylin and Eosin (Mag. With exception of low doses that showed normal morphology of the hepatocyte and sinusoid that is not infiltrated, high doses of extract greater than 500mg/kg showed mild fat congestion in the central venules with liver parenchyma showing area of hemorrhage compared to the control. Make sure to follow the package instructions carefully. This later condition is termed insulin resistance. The package will tell you exactly how, when, and how much feed to use. One of the side-effects of some orthodox drugs used in the past had been excessive inhibition of the carbohydrate-hydrolyzing enzymes, which in turn leads to abdominal discomfort and. Side effects of Ewe eje (Justicia carnea leaf Side Effects). Justicia carnea (Brazilian Plume) is an upright, evergreen shrub with large, dark green leaves, 10 in. Daily intake of the Ewe eje or ajeri can increase the absorption of iron and vitamins, Uses and health benefits of Ewe eje (Justicia carnea leaf). Prevent this by spraying the leaves with water. The Brazilian Plume is native to mainly tropical areas in South America, meaning it thrives in warm and slightly humid climates. This is due to the inability of the pancreatic beta cells to secrete insulin, which transports glucose to cells, or the inability of cells of the body to recognize insulin. Haematological and biochemical studies on Justicia carnea leave extract in phenylhydrazine induced-anemia in albino rats. The result of hematology indices is presented in Table3. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. The significant increase in MDA level at 1200mg/kg might be due to the presence of active secondary metabolites in the extracts that could have acted as prooxidant. These antibodies help prevent infections and fight off diseases. It is also known as Jacobinia carnea, and is a part of the Acanthaceae family along with the Aphelandra squarrosa (Zebra plant) and Crossandra. Consumption of medicinal plants has diverse therapeutic benefits and could also have toxic effect. No. Oral acute toxicity study on J. carnea ethanol extract (JCEE) was carried out according to Lorke [15] method using the total of twelve (12) albino rats in two phases. In an acute exposure of experimental rats to single oral doses of extract, no mortality and signs of adverse effects were observed. Justicia carnea (Brazilian Plume) - Gardenia.net Nutritive properties of aqueous extract Justicia carnea leaves and its Effect of the ethanol extract of Justicia carnea leaves on the red Decoction of ewe eje or its leaf extract can lower serum cholesterol and get rid of bad cholesterol (LDL). All authors read and approved the final draft of the manuscript. The non significant decrease observed in this study is in consonance with the work of Onyeabo et al., [9] who also reported no significant difference in the relative weights of liver and kidney. Side Effects, Uses and Health benefits of Ewe eje (Justicia carnea leaf), The exact topic of this article first appeared on www.nimedhealth.com.ng. Join now and start creating your dream garden! Justicia carnea needs bright, indirect light to thrive. Filed in Biochemistry Project Topics, Current Projects by TMLT Editorials on September 22, 2020. Differences between means were considered to be significant at (p<0.05) using LSD (Least Square Difference) post hoc test. Correspondence to CAS The Justicia carnea leaves are rich in B-vitamins. 1. Aim. Although, medically, it is advised you see your doctor or a physician before using the leaf for medicinal uses. Cut back after flowering to 2-3 nodes from the ground to keep the plant bushy and promote new blooms. Free radicals and antioxidants in normal physiological functions and human disease. 2002;82:197205. https://doi.org/10.1186/s40816-020-00234-4, DOI: https://doi.org/10.1186/s40816-020-00234-4. Vitamin B aids in the formation of red blood cells and helps to build tissues. Keep an eye out for glasshouse red spider mite and glasshouse whitefly. It is an awesome plant and worth your time and attention. long (25 cm), and showy flower plumes, 8 in. (2017). Contamination of medicinal plant could be as a result of contaminants (such as heavy metals, aflatoxin and pathogenic microbes) from soil and manner of herbal preparations [4]. During the growing season, the justicia (plant) should be watered thoroughly with room temperature water. Consumption of medicinal plants without scrutinizing its efficacy and safety can result in unexpected toxic effects resulting in physiology changes of different organs in the body. These minerals help in boosting blood production, which is why the plant is called ogwu obara (blood medicine) among the Igbo people of Southern Nigeria. Generic and epigenetic contributions to human nutrition and health: managing genome-diet interactions. Prof. F.O. https://doi.org/10.4314/njps.v19i1.32627. It is nicknamed the Blood leaf, Blood of Jesus, and Jehovah Witness leaf in Nigeria, and is a widely used leaf across states in Nigeria. 1978;90:819. It is very rich in iron, a major component is RBC hemoglobin. The species Justicia secunda Vahl belongs to the family - Acanthaceae - together with up to 600 other shrubs and herbs species. Although, medically, it is advised you see your doctor or a physician before using the leaf for medicinal uses. Mr. T.S. The plume flowers grow atop a crown of foliage in large dense clusters. 2012; 22(1):220238; https://doi.org/10.1590/S0102-695X2011005000196. 1978;52:30210. They should be watered regularly (once per week), but not overwatered. Google Scholar. Molecules (Basel, Switzerland), 19(12), 2144221461. Duan WL, Liang XM. Infertility after therapy, in particular, imposes a significant mental strain on young patients. 2018;2018:5762368. While histology of organs showed no adverse pathological lesions in the internal organs of rats, higher dose (1200mg/kg) over a period of time could cause noticeable liver and kidney injury. However, coadministration of both extracts exerts a synergistic effecton the . Rather it can assist with improveing liver function such as detoxification. Further study assessing the kidney indices (urea, creatinine and electrolytes) is however encouraged to ascertain the safety of the plant extract on renal function. PDF Haematological and Biochemical Studies on Justicia Carnea Leaves In some areas, the plant may tolerate temperatures as low as 50 degrees Fahrenheit (10 C). Diallo A, Gbeassor M, Vovor A, Eklu-Gadegbeku K, Aklikokou K, Agbonon A. Ewe eje is safe and healthy for consumption. Superoxide dismutase was carried out using the method of Sun and Zigma [18]. 1983;53:27589. Local consumers of the leaves are mostly . The mixture was incubated at 28C for 30min and the absorbance read at 550nm against the reagent blank. Data were analyzed using one-way analysis of variance (ANOVA) using Statistical Product and Service Solutions (SPSS) version 17.0 and results were expressed as meanSEM. Acute toxicity was determined in two phases using Lorke method. A multidisciplinary overview of intoxicating snuff rituals in the western hemisphere. Create a membership account to save your garden designs and to view them on any device. 2007;112(1):13844. There are several claims that justicia carnea can prevent epilepsy and convulsion among children. The plant possess several bioactive compounds like polyphenols, which act as antioxidants or anti-inflammatory compounds. In Nigeria, the leaf of Justicia carnea is usually prepared with edible vegetables to make soup, boiled separately in water to make tea or prepared by cooking with other medicinal plants for therapeutic purposes. The spectacular rosy plumes of the flamingo-colored flower are distinctive and attract hummingbirds to pollinator gardens. Safety assessment of oral administration of ethanol extract of Justicia Oyenihi OR, Brooks NL, Oguntibeju OO. Saunders; 1995. p. 26873. We currently have no information for JUSTICIA PECTORALIS overview. 2005 - 2023 WebMD LLC, an Internet Brands company. It is cultivated and sold as a decorative potted plant and is planted in landscaping as a feature plant in warm . Medapa S, Singh GRJ, Ravikumar V. The phytochemical and antioxidant screening of Justicia wynaadensis. 2016;4(1):5360. The renal effects of blood glucose-lowering plant-derived extracts in diabetes mellitus-an overview. However, serious caution of the dose should be taken into consideration when extrapolating this result for human consumption. Clin Phytosci 7, 2 (2021). II. However, scientifically it is called Justicia carnea. How Justicia Betonica is effective for various diseases is listed in repertory format. The Portal triad (blue arrow) composed of the hepatic vein and artery as well as the bile duct (PT), the well distributed hepatocytes (H) (yellow arrow) and hepatic sinusoids (black arrow) are demonstrated across study groups. As declared by all authors, no competing interests exist. Another strong benefits of justicia carnea leaves is in lipid profile. When you boil the plant, it turns the water red. Cassani, J., Dorantes-Barrn, A. M., Novales, L. M., Real, G. A., & Estrada-Reyes, R. (2014). Section of livers and kidneys were excised and fixed in 10% formalin for histopathology examination. Anti-depressant-like effect of kaempferitrin isolated from Justicia spicigera Schltdl (Acanthaceae) in two behavior models in mice: evidence for the involvement of the serotonergic system. 10.9734/ijbcrr/2020/v29i630194. [1] The perennial plant is native to the Atlantic Forest ecoregions of eastern Brazil . Maturitas 2010;66(3):315-322. When properly boiled in water, the aqueous leaf extract turns red, and when mixed with milk turns pink. Justicia carnea [jus-TEE-see-ah, KAR-nee-uh] is popularly known as the Brazilian Plume Flower. 2003;66:1499503. Histopathological examinations of sections of the liver collected from the 4 Hence, the use of Justicia carnea leaves may help reduce your risk of heart diseases, heart attack, stroke etc. Aim. Acta Sci Pol Technol Aliment. Each rat was dissected and blood samples were collected by cardiac puncture using 5mL into tubes containing ethylenediaminetetraacetic acid (EDTA) for hematological analysis. Higher doses (>500mg/kg) of extract significantly (p<0.05) increased RBC, hemoglobin and platelet compared to the control. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. Lorke D. A new approach to practical acute toxicity testing. 2005;102(2):197201. PDF Effects of Ethanol Leaf Extract of Justicia Carnea on Biochemical 32 years old (Greco et al., 1974), long-term treatment side effects are becoming more critical. Previously, J. carnea leaf has been reported to contain high quantity of phytochemical constituents (such as saponins, alkaloids and terpenoids), vitamins (A, C and E) and minerals [9, 10]. Briefly, 1.0ml of the sample was mixed with 2ml of TCA-TBA-HCl reagent (0.37% thiobarbituric acid, 15% trichloroacetic acid and 0.24N HCl in 1:1:1) and boiled at 100C in a water bath for 15min. One of the health benefits of justicia carnea is in boosting immune system. Biochemistry Unit, Department of Chemical Sciences, Olusegun Agagu University of Science and Technology, Okitipupa, Nigeria, Emmanuel Sina Akintimehin,Kayode Olayele Karigidi,Tope Samuel Omogunwa&Foluso Olutope Adetuyi, You can also search for this author in Except the group that received 1200mg/kg JCEE which showed significant (p<0.05) elevation of SOD and MDA in the liver, other doses (<1200mg/kg) demonstrated no significant difference compared to the control. Once the roots have established, adjust watering to three to five days apart. This may be because of its hepatoprotective activity. Ani, Onuabuchi & Udedi, Stanley & Asogwa, Kingsley & Enemali, Michael & Onwelumadu, Chigozie & Ikedife, Kenneth. Ewe eje as a Natural Blood booster/tonic: Due to the high concentration of iron in this leaf, it can help boost blood production by increasing the red blood cells, haemoglobin, and the blood platelets. Braz. In conclusion, oral acute administration of J. carnea ethanol extract is safe because neither mortality nor any signs of toxicity were observed in experimental rats. Faiza R, Waqas KK, Adeel M, Muhammad G. Detection of bioactive fractions of Justicia adhatoda leaves. Microsomal lipid peroxidation. Effect of Tectona grandis on phenylhydrazine induced anemia in rats. Despite the avalanche use of medicinal plant, preliminary toxicity studies remain essential tools to ensure safe consumption and prevent unexpected toxicity that could arise from long term exposure. (2020). Pot the specimen and bring it indoors to add a bright touch of color to your interiors. The appropriate dose of Justicia pectoralis depends on several factors such as the user's age, health, and several other conditions. de Smet, P. A. 400). Badami S, Aneesh R, Sankar S, Sathishkumar MN, Suresh B, Rajan S. Antifertility activity of Derris brevipes variety coriacea. Anyone you share the following link with will be able to read this content: Sorry, a shareable link is not currently available for this article. In phase I, rats were randomized into 3 groups of 3 rats per group. Paradoxically, oxidation of GSH has been reported to occur when GSH interact with metal ions thereby generating superoxide anions from the transfer of electrons from the metal ions to molecular oxygen [32]. View abstract. Haematoxic effects following ingestion of Nigerian crude oil and crude oil polluted shellfish by rats. They range in colors such as red, orange, mauve, magenta, apricot, and pink. Consequently, the effects of the extract on MDA level could indicate damage to cell membrane lipids of the hepatocyte which could result to increased generation of reactive oxygen species (ROS). J Med Plants Res. Tissues were processed automatically using automatic tissue processor (Leica TP 1020) and allowed to pass through varying percentage of alcohol and absolute alcohol for the purpose of dehydration following dewaxing in Xylene for 15mins. Regular intake can reduce your risk of liver diseases like liver cirrhosis, hepatitis and liver inflammation. J Am Diet Assoc. Liver superoxide dismutase (SOD) activity was significantly (p<0.05) increased at 1200mg/kg while other tested doses caused no detrimental effect on glutathione, catalase, SOD and malondialdehyde level in liver and kidney. From mild to severe order, the graded doses showed distorted renal cortex with collapsed renal glomeruli and dillated capsular spaces. Proximate analysis of the aqueous extract of J. carnea leaves showed that it contains appreciable amounts of 53.07 0.07% carbohydrate, 9.26 0.02% ash, and 26.71 0.02% . 2003;84:99104. Control treatment showed normal central venules without congestion, the morphology of the hepatocytes appear normal, the sinusoids appear normal with no observable form of infiltration and no observable pathological lesion seen. OTHER NAME(S): Achille Millefeuille, Achille Mille-Feuille, Ana. Note this is the default cart. Yes my readers. de Vries, J. X., Tauscher, B., and Wurzel, G. Constituents of Justicia pectoralis Jacq. The roots and the leaves possess medicinal values and have been used in treating several diseases. The fresh leaves were thoroughly washed under running tap, air dried under shade, pulverized and extracted with ethanol. Eyong EU, Umoh IB, Ebong PE, Eteng MU, Antai AB, Akpa AO. Justicia Betonica Herb Uses, Benefits, Cures, Side Effects, Nutrients Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. Sample (or standard solution) (0.01ml) was mixed with diluted (1:4v/v distilled water) biuret reagent (100mM sodium hydroxide, 16mM sodium-potassium tartrate, 15mM potassium iodide and 6mM copper sulphate). Tags: benefits of justicia carnea, health benefit of justicia carnea, justicia carnea . https://doi.org/10.1016/j.biocel.2006.07.001. Prepare the existing soil by breaking it up with a spade or hoe. Growing up, we were told many biblical stories, Negro pepper (Xylopia aethiopica) is a spice plant that possess several health benefits, which make it an indispensable, Eating for its sour taste when fairly ripen and sweet taste when well ripen, star apple finds favor, Fertility tree (Newbouldia laevis), also known as boundary tree, Ogirisi in Igbo, Adikuru in Hausa and Ewe akoko, Guava (Psidium guajava) is a well known tropical tree which is widely grown for its fruits. Cookies policy. He earned B.Sc. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. 2013;1:38898. You can add the leaves and water altogether in a pot and allow to boil till the water turns red. The Hematological system and antioxidant status of rats following 14days of sub-acute exposure tolerated the ethanol extract of J. carnea leaf. PDF Biomedical Research 2019; 30 (4): 645-654 ISSN 0970-938X - Allied Academies https://doi.org/10.1016/j.jep.2005.06.013. 2008; 10:2. In-vitro Antioxidant Screening of Ethanol Extracts of Costus afer and 50mg/kg-1200mg/kg treatment relative to control treatment showed varied degree of renal injury that is dose dependent. CAS For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. The plant produces dark green leaves around 8 inches in length. Hepatoprotective Effect of Methanol Extract of Justicia carnea Leaves Cardioprotective role of Justicia traquebareinsis Linn. READ ALSO: How long does it take for Aju mbaise to work. Justicia carnea is a medicinal plant that is used conventionally as blood tonic from time immemorial in Nigeria. In this article i will take you through the nutritional and medicinal benefits of justicia carnea. PubMedGoogle Scholar. Detection of Bioactive Fractions of Justicia Adhatoda L. Leaves Excitedly, scientific studies have supported the traditional claims. Clinical Guide to Laboratory tests. https://doi.org/10.35841/biomedicalresearch.30-18-666. Rich on haematological and biochemical parameters in healthy Wistar rats. The catalase activity was calculated using the expression: Note: A=change in absorbance, TV=total volume, TP=total protein, SV=sample volume, =molar extinction=40M1 cm1. Ewe eje is mainly given to persons who want a blood boost such as pregnant women, persons suffering from anemia and other convalescents. Studies have shown that ewe eje contains antioxidant and cardio-protective properties. This claim have not been verified. The aim of this study is to evaluate the safety of ethanol extract of J. carnea leaf assessing the hematology indices, organ antioxidant system and histology in healthy male wistar rats. The blood stimulating effects could be due to the presence of dietary bioactive constituents that stimulate activities of haematopoietic cells and stabilization of blood in circulation [21]. Aim. So lets go through this together. Chidubem Olovo is a biochemist and a researcher whose interest is centered on the chemistry of natural products, their pharmacological properties and how using the plant sources can improve human healthy living. Methods. Feed the soil when the cutting is new to encourage better growth. The liver and kidney of rats administered with 500mg/kg JCEE and above demonstrated slight increase in MDA level with significant (P<0.05) increase only observed in the liver of rats that received 1200mg/kg of extract. WebMD does not provide medical advice, diagnosis or treatment. Justicia Carnea leaves extract contains a rich supply of iron, riboflavin, vitamins A, C, E, B1, B2, B9, and B12. Packed cell volume (PCV) and mean corpuscular volume (MCV) in treated rats with JCEE were statistically unperturbed compared to the control. The indistinguishable differences of total protein in the liver and kidney of rats treated with ethanol extract of J. carnea could indicate that the plant extract did not alter protein synthetic function of the organs. Deleting this collection CANNOT be undone. Due to the local availability, easy access and relatively low cost, medicinal plants are gaining attentions in health care programmes. Despite the therapeutic importance of medicinal plants, toxic substances have been shown to be present in large numbers of plants investigated [3]. Summarily, experimental group shows some degenerative changes that can be termed as necrosis, some mild fibrosis and hemorrhage characterized by the presences of infiltrated red hemorrhagic and inflammatory cells. It creates the perfect environment for aphids and dried sod. J Ethnopharmacol. The principle is based on the reduction of dichromate in a weak acid medium (acetic acid) to chromic acetate which is further heated in the presence of hydrogen peroxide to form an unstable intermediate (perchromic acid) that can be monitored spectrophotometrically at 620nm. Part shade is the ideal growing condition for Brazilian plumes. Justicia carnea does not cause miscarriage or congenital birth defects. Leal, L. K., Ferreira, A. The haematological indices of the blood samples were determined using an automated URIT 2900 Plus 3 Differential Haematological Analyzer. Furthermore, increased MID by the extracts could indicate macrophage formation ability and pathogenic scavenging role. In its native habitat, the Justicia carnea plant grows upright and may reach 3 5 feet tall. Summer temperatures above 77 degrees Fahrenheit (25 C) are perfect. Grows up to 4-6 ft. tall (120-180 cm) and 2-3 ft. wide (60-90 cm). Plantcaretoday.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to amazon.com, how to get rid of leaf eating caterpillar. B-vitamins are good sources of energy. One of the oldest known plant is the fig tree. This lends the plant some interesting names such as Blood of Jesus plant and Hospital too far. Results obtained from the acute oral toxicity study revealed tolerance of experimental rat to acute administration of J. carnea ethanol extracts since no mortality and signs of toxicity were observed after 24h (Table1). View abstract. The renal tubules and interstitial spaces appears distorted with presence of red inflammatory cells infiltrating the renal interstitial spaces as well as focal sclerosis of renal glomeruli with associated degeration of the glomerular membrane. Exactly 1.0ml of tissues (liver and kidney) was deproteinised using 0.1ml of 10% TCA and centrifuged at 650g for 5min to obtain supernatant. Fresh leaves of Justicia carnea were collected from Okitipupa area Ondo State. The Health benefit of Ewe eje (Justicia carnea leaf) are highlighted in this article. The findings show that ethanol extracts of Costus afer and Justicia carnea could operate as main antioxidants and free radical scavengers. A cup of water 2013;3(4):1248 https://doi.org/10.7324/JAPS.2013.3422. et al. Why urban citizens in developing countries use traditional medicines: the case of suriname. The liver and kidneys were excised and rinsed immediately in a normal saline (0.9% Nacl) to remove blood stain, dried between layers of Whatman filter paper, weighed and homogenized to obtain the supernatant for biochemical analysis. Cookies, This site is protected by reCAPTCHA and the Google, Justicia scheidweileri (Purple Shrimp Plant), Justicia americana (American Water-Willow), Want Garden Inspiration? Google Scholar. I am a practicing medical doctor, a philosopher, critical thinker, a globalist, a patriot, SEO expert and a patient blogger. Paes-Leme AA, Motta ES, De Mattos JCP. J Ethnopharmacol. Anal Biochem. Canadian J Appl Sci. 3 The plants in the family are reported to have CNS effects which are exploited in the management of epilepsy, other mental disorders, headache and fever, probably due to their sedative and analgesic properties. Evid Based Complement Alternat Med. View abstract. 2007;39(1):4484. In this study, the aqueous leaf extract of Justicia carnea was used. Significant (P<0.05) decrease observed in liver total protein of rat administered with 1200mg/kg of extract could be due to intrinsic factors in-vivo that might not necessarily indicate adverse reaction of the extracts. Group 2, 3, 4, 5, 6 were respectively administered orally with 50, 100, 500, 800 and 1200mg/kg body weight of JCEE once daily for 14days using an oral gavage. Phytochemical screening and Gas Chromatography-Mass Spectrometry (GC-MS) analysis indicated presence of . This plant is somewhat drought-tolerant once established but looks best with regular watering during periods of extended dry weather. Effects of ethanol leaf extract of Justicia carnea on serum SOD View abstract. 3. In a pot, pour in a cup of water and bring to a boil. Mean lethal dose of the extract was found to be above 5000mg/kg body weight (bw). J Afr Ass Physiol Sci. Read also (Cashew leaves: health benefits and side effects of Anacardium occidentale). How long does it take for Aju mbaise to work. The plant is transplanted in the spring. In traditional medicine, justicia carnea is used in treating hepatitis. Tropical habitats mean constant moisture. Antioxidants & redox signaling Forum Review. SOD activity was determined by its ability to inhibit the auto-oxidation of epinephrine determined by the increase in absorbance at 480nm. Justicia carnea and Cnidoscolus aconitifolius were tested for their capacity to ameliorate the fecundity of chloramphenicol-induced lymphoma in rats. The Pros and Cons of Creatine You Should Know. -Amylase binding-interaction with JCAE was also investigated using fluorescence spectroscopy and molecular docking. Mr. K.O. The acute toxicity test also proved that justicia carnea leaves are safe for consumption. Google Scholar. Washington, DC: The National Academies Press; 1997. https://doi.org/10.17226/4988. While graded doses of J. carnea ethanol extract showed no significant difference in the liver and kidney GSH compared to the control, only rats that received 1200mg/kg body weight JCEE statistically decreased in the kidney. long (20 cm), densely packed with pink to crimson tubular flowers.
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